MHP's DARK RAGE - The Next Generation Pre-Workout Formula For Extreme Muscle Pumps, Power And Performance
MHP's Dark Rage introduces a new pump inducing technology that goes far beyond nitric oxide. Compounds called Erythropoietin (EPO) Stimulating Agents are being used by bodybuilding's elite to induce muscle pumps and muscle growth far beyond nitric oxide or anything else ever used. The truth is that a pump is the result of delivering more blood to muscle tissue, so while the use of nitric oxide stimulating ingredients like AAKG and Arginine are somewhat effective by causing vasodilation, they do not increase blood volume. MHP's research and development team set out to formulate a product that would far surpass all others in not only pumps, but also in energy, workout intensity, muscle power, muscle endurance, muscle growth and recovery. Dark Rage's dual erythropoietin –nitric oxide action causes what scientists call "hemodynamic blood plasma vasodilation". What this means is a larger supply of EPO induced blood is simultaneously being transported through nitric oxide induced vasodilated veins and capillaries to muscle tissue.This increased blood supply not only increases the size and effects of the muscle pump, but it also has a profound anabolic muscle building effect as it engorges your muscle tissue with Dark Rage's other active ingredients like creatine, beta-alanine, BCAAs, AAKG, Arginine and many more.
The Science Behind EPO and Muscle Growth
EPO is a hormone that controls erythropoiesis, or red blood cell production. It also has other known biological functions. Erythropoietin has traditionally been thought of as an endurance doping agent as it enhances red blood cell production which enhances oxygen being carried to muscle tissue. EPO is directly associated with red blood cell production and blood volume. Recently, researchers have discovered another function of EPO; it has the ability to enhance muscle recuperation and muscle growth.
- EPO receptors are found in skeletal muscle, activation of the EPO receptor in muscle stimulates the activator of a protein called STAT5; STAT5 also activates the PI3 kinase-Akt signaling pathway, which is believed to result in activation of AKT and p70s6K, which in turn plays a role in protein synthesis1,2 . This pathway has been suggested to be critical in regulation of skeletal muscle hypertrophy3, 4. On the basis of the above findings it appears plausible that EPO receptor activation may contribute in regulating skeletal muscle fiber growth.
- A single injection of EPO results in very high plasma EPO concentrations which increases MRF4 (muscle regulatory factor is part of a family of genes conducive to muscle growth) content for hours after injection, MRF has been shown to be a part of the genes related to muscle fiber growth as resistance exercise has been shown to increase MRF4 mRNA in human skeletal muscle as well5.
- In this month's Journal of Orthopaedic Research, researchers caused muscle damage in rats and administered EPO. The researchers concluded that, "EPO results in faster and better regeneration of skeletal muscle tissue after severe trauma and goes along with improved microcirculation. Thus, EPO, a compound established as clinically safe, may represent a promising therapeutic option to optimize the posttraumatic course of muscle tissue healing."6
Mind Blowing Pumps, Increased Strength, Maximum Muscle Growth, Extreme Energy and Intensity! DARK RAGE is ALL of The ABOVE and MORE!Dark Rage goes beyond the PUMP and has 6 Formula's In One Container making it the most comprehensive pre-workout supplement to date!
Epodrol™: Epo Plasma Red Blood Cell Stimulator
A patent pending compound of clinically researched EPO co-factors designed to trigger the powerful hormone Erythropoietin to increase the production of red blood cells and increase plasma blood volume for far greater muscle pumps and vascularity. This increased blood volume in turn increases oxygen transport and the delivery of anabolic hormones and nutrients to muscle tissue, which has an immediate impact on muscle pumps, performance and stimulating muscle growth. EPODROL features proven EPO and red blood cell producing ingredients such as, Arachidonic Acid, Echinacea, Cobalt, Albumin, Iron and a matrix of essential vitamin and mineral blood building cofactors.
Hemastem™: Hematopoietic Stem Cells Stimulator
This ultimate innovation contains research proven ingredients that stimulate the production of the stem cells, which are the precursor cells that are activated by EPO to develop into full fledged red blood cells. HEMASTEM makes the EPO simulating effects of DARK Rage even more effective in boosting red blood cells and increasing blood volume for extreme vascular expansion and muscle pumps. HEMASTEM features proven stem cell stimulating ingredients such as, Cyanophyta, Angelica, Ginkgo, Anthocyanins, Polyphenols, and essential vitamin and mineral nutrients.
Vasoshock-No™: Nitric Oxide (No) Mass Pump Infusion
The most advanced and only nitric oxide complex with Hemafolate designed to override NO agonist and push NO beyond normal physiological levels for greater vasodilation. This proprietary blend of compounds promotes maximally effective nitric oxide (NO) induced vasodilation and muscle pumps through a series of complex NO producing bio-chemical pathway synergists. This extra vascular expansion is critical to improve blood viscosity to support DARK Rage's increased blood volume and enhance blood flow rate for maximum muscle pumps. VASOSHOCK-NO features proven NO elevating ingredients, such as the special multi-arginine complex (AAKG, Di-Arginine Malate, L-Arginine, Arginine Ethyl Ester), Citrulline, Gynostemma, Pycnogenol, Cnidium, Icarin and Hemafolate.
Myovol-Atp™: Advanced Multi-Phase Creatine Transport And Cell Volumizing Matrix
This cutting-edge matrix works synergistically to accelerate creatine transport directly into working muscle tissue, along with delivery of vital metabolic cofactors to produce extreme muscle bioenergetics for increased strength and muscle fiber enlargement. MYOVOL-ATP features proven cell volumizing and bio-energetic boosting ingredients, such as Glucose Bound Creatine Gluconate, Creatinol-O-Phosphate, MicroTein sustained release creatine, Glycocyamine, GuaniPro guanidine propionic acid and TMG.
Betaendure™: Muscle Endurance Beta Alanine/Ph Buffering System
A key factor for enhancing muscle strength and stimulating muscle growth is optimizing the anaerobic bio-energetic fast-twitch muscle fiber capacity to contract over and over again during heavy weight training. BETAENDURE contains an advanced muscle pH buffering system that actually enables you to fight off muscle fatigue so you can squeeze out more reps and pump even more anabolic blood into your muscles during your totally outrageous "overload" training sessions. BETAENDURE features proven fatigue fighting and anti-catabolic ingredients such as, Beta Alanine, Citrate, Phosphate, Taurine and BCAAs.
Psychorage™: Extreme Focus And Energy Up Regulators
Get ready to experience the most intense, energized workout of your life as exclusive psychotropic factors, neuro-active compounds and energizers found only in Dark Rage ignite extremely powerful neural system impulses. PSYCHORAGE triggers an extreme state of euphoria and mental focus while stimulating the release of adrenaline to super-charge your workouts.PSYCHORAGE features proven neuro-active ingredients, such as Glucuronolactone, Caffeine, 1-amino-2-phenylethane, Beta Methoxyphenylethylamine, Tyrosine, Hyperzine A, Vinpocetine, Theobromine and Yohimbe.
Dark Rage sets a new scientific standard of pre-workout supplementation with exclusive EPO Blood Doping Technology™ and an amazingly powerful combination of advanced, next generation ingredients designed to take your workouts to an entirely new level of intensity, increased strength, extreme muscle growth, incredible anabolic muscle pumps and fast recovery!
Feel the Power of DARK RAGE and Experience the Ultimate Workout!
Here the live interview about Dark Rage with Gerard Dente at the MD website!
- Ratajczak J, Majka M, Kijowski J, Baj M, Pan ZK, Marquez LA, Janowska-Wieczorek A, Ratajczak MZ. Biological significance of MAPK, AKT and JAK-STAT protein activation by various erythropoietic factors in normal human early erythroid cells. Br J Haematol 115: 195-204, 2001.
- Deng L, Sowers JR, Cutaia MV, El Sherif N. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway. Biochem Biophys Res Comm 308: 990-;994, 2003.
- Bodine SC, Stitt TN, Gonzalez M, Kline WO, Stover GL, Bauerlein R, Zlotchenko E, Scrimgeour A, Lawrence JC, Glass DJ, Yancopoulos GD. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol 3: 1014- 1019, 2002.
- Rommel C, Bodine SC, Clarke BA, Rossman R, Nunez L, Stitt TN, Yancopoulos GD, Glass DJ. Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways. Nat Cell Biol 3: 1009-1013, 2001.
- Psilander N, Damsgaard R, Pilegaard H. Resistance exercise alters MRF and IGF-I mRNA content in human skeletal muscle. J Appl Physiol 95: 1038-1044, 2003.
- Erythropoietin improves functional and histological recovery of traumatized skeletal muscle tissue. Rotter R, Menshykova M, Winkler T, Matziolis G, Stratos I, Schoen M, Bittorf T, Mittlmeier T, Vollmar B. J Orthop Res. 2008 Dec;26(12):1618-26.